Abstract

The benefits of previously improved blood-pressure control were not sustained when between-group differences in blood pressure were lost. Early improvement in blood-pressure control in patients with both type 2 diabetes and hypertension was associated with a reduced risk of complications, but it appears that good blood-pressure control must be continued if the benefits are to be maintained. (UKPDS 81; Current Controlled Trials number, ISRCTN75451837.)

Keywords

MedicineBlood pressureDiabetes mellitusUnited Kingdom Prospective Diabetes StudyType 2 diabetesMyocardial infarctionRandomizationClinical endpointStroke (engine)Randomized controlled trialInternal medicineClinical trialSurgeryPediatrics

MeSH Terms

AgedAntihypertensive AgentsCardiovascular DiseasesDiabetes MellitusType 2Diabetic AngiopathiesFemaleFollow-Up StudiesHumansHypertensionKaplan-Meier EstimateMaleMiddle AgedRiskSurveys and Questionnaires

Affiliated Institutions

Related Publications

Publication Info

Year
2008
Type
article
Volume
359
Issue
15
Pages
1565-1576
Citations
761
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

761
OpenAlex
14
Influential
601
CrossRef

Cite This

Rury R. Holman, Sanjoy K. Paul, M. Angelyn Bethel et al. (2008). Long-Term Follow-up after Tight Control of Blood Pressure in Type 2 Diabetes. New England Journal of Medicine , 359 (15) , 1565-1576. https://doi.org/10.1056/nejmoa0806359

Identifiers

DOI
10.1056/nejmoa0806359
PMID
18784091

Data Quality

Data completeness: 86%