Rury R. Holman - Researcher Profile | RDL Research Database

Publications

3 shown

Insulin deficiency and insulin resistance interaction in diabetes: Estimation of their relative contribution by feedback analysis from basal plasma insulin and glucose concentrations

R. C. Turner , Rury R. Holman , David R. Matthews +2 more

1979 Metabolism 388 citations

United Kingdom Prospective Diabetes Study 24: A 6-Year, Randomized, Controlled Trial Comparing Sulfonylurea, Insulin, and Metformin Therapy in Patients with Newly Diagnosed Type 2 Diabetes That Could Not Be Controlled with Diet Therapy

Alex Wright , C A Cull , Rury R. Holman +24 more

Because initial insulin therapy induced more hypoglycemic reactions and weight gain without necessarily providing better control, it may be reasonable to start with oral agents ...

1998 Annals of Internal Medicine 388 citations

Approach to maintaining comparability of biochemical data during long-term clinical trials.

C A Cull , Susan E. Manley , Irene Stratton +5 more

Our objective was to design a structured approach to maintaining comparability of biochemical data during a long clinical trial. Maintaining the comparability of clinical and bi...

1997 PubMed 28 citations