Intragenic ERBB2 kinase mutations in tumours

Philip Stephens; Chris Hunter; Graham R. Bignell; Sarah Edkins; Helen Davies; Jon W. Teague; Claire Stevens; Sarah O’Meara; Raffaella Smith; Adrian G. Parker; Andy Barthorpe; Matthew J. Blow; Lisa Brackenbury; Adam P. Butler; Oliver B. Clarke; Jennifer Cole; Ed Dicks; Angus Dike; Anja Drozd; Ken Edwards; Simon Forbes; Rebecca R. Foster; Kristian Gray; Chris Greenman; Kelly Halliday; Katy Hills; Vivienne Kosmidou; Richard Lugg; Andy Menzies; Janet Perry; Robert Petty; Keiran Raine; Lewis Ratford; Rebecca Shepherd; Alexandra Small; Yvonne Stephens; Calli Tofts; Jennifer Varian; Sofie West; Sara Widaa; Andrew Yates; Francis Brasseur; Colin S. Cooper; Adrienne M. Flanagan; Margaret A. Knowles; Suet Yi Leung; David N. Louis; Leendert H. J. Looijenga; Bruce Malkowicz; Marco A. Pierotti; Bin Tean Teh; Georgia Chenevix‐Trench; Barbara L. Weber; Siu Tsan Yuen; Grace Harris; Peter Goldstraw; Andrew G. Nicholson; P. Andrew Futreal; Richard Wooster; Michael R. Stratton

doi:10.1038/431525b

Keywords

Lung cancerCancer researchProtein kinase domainGeneTyrosine kinaseMutationBiologyAdenocarcinomaCyclin-dependent kinase 4KinaseReceptor tyrosine kinaseCancerGeneticsProtein kinase AMedicineCyclin-dependent kinase 2Signal transductionOncologyMutant

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Publication Info

Year: 2004
Type: article
Volume: 431
Issue: 7008
Pages: 525-526
Citations: 777
Access: Closed

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APA Style

                            
                                
                                    Philip Stephens, 
                                
                                    Chris Hunter, 
                                
                                    Graham R. Bignell
                                
                                et al.
                            
                            (2004). 
                            Intragenic ERBB2 kinase mutations in tumours. 
                            Nature
                            , 431
                            (7008)
                            , 525-526.
                            https://doi.org/10.1038/431525b
                        

Identifiers

DOI: 10.1038/431525b

Intragenic ERBB2 kinase mutations in tumours

Keywords

Affiliated Institutions

Related Publications

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of <i>ERBB2</i>

EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib

Acquired Resistance to Epidermal Growth Factor Receptor Kinase Inhibitors Associated with a Novel T854A Mutation in a Patient with <i>EGFR</i>-Mutant Lung Adenocarcinoma

<i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

Molecular Target Class Is Predictive of <i>In vitro</i> Response Profile

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