Institute of Cancer Research

Mutations of the BRAF gene in human cancer

Signatures of mutational processes in human cancer

The cancer genome

DNA methylation-based classification of central nervous system tumours

Tumour necrosis factor and cancer

The landscape of cancer genes and mutational processes in breast cancer

All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer clonal selective advantage on cancer cells and are causally implicated in oncog...

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations

Our study has identified key features of the histologic phenotypes of breast cancers in carriers of mutant BRCA1 and BRCA2 genes. This information may improve the classification...

Floating absolute risk: An alternative to relative risk in survival and case‐control analysis avoiding an arbitrary reference group

Abstract We discuss the problem of describing multiple group comparisons in survival analysis using the Cox model, and in matched case‐control studies. The standard method of co...