Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes

Abstract

Among patients who have recently had an acute coronary syndrome, an intensive lipid-lowering statin regimen provides greater protection against death or major cardiovascular events than does a standard regimen. These findings indicate that such patients benefit from early and continued lowering of LDL cholesterol to levels substantially below current target levels.

Keywords

MedicineAtorvastatinPravastatinHazard ratioAcute coronary syndromeUnstable anginaMyocardial infarctionLiterInternal medicineConfidence intervalRegimenClinical endpointStatinCardiologyCholesterolRandomized controlled trial

MeSH Terms

AnginaUnstableAnticholesteremic AgentsAtorvastatinCardiovascular DiseasesCholesterolHDLCholesterolLDLFemaleHeptanoic AcidsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedMyocardial InfarctionPravastatinProportional Hazards ModelsPyrroles

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Publication Info

Year: 2004
Type: article
Volume: 350
Issue: 15
Pages: 1495-1504
Citations: 4868
Access: Closed

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APA Style

                            
                                
                                    Christopher P. Cannon, 
                                
                                    Eugene Braunwald, 
                                
                                    Carolyn H. McCabe
                                
                                et al.
                            
                            (2004). 
                            Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes. 
                            New England Journal of Medicine
                            , 350
                            (15)
                            , 1495-1504.
                            https://doi.org/10.1056/nejmoa040583
                        

Identifiers

DOI: 10.1056/nejmoa040583
PMID: 15007110

Data Quality

Data completeness: 86%