Abstract
Twenty years ago the concept that immunological mechanisms might regulate carcinogenesis was highly controversial. Today this concept survives in modified form and continues to evolve as our knowledge of the immune system, the etiology of cancer, and tumor antigens expands. This review illustrates how our ideas about immune surveillance have changed in recent years and considers the significance of these changes for the future directions of cancer immunobiology.
Keywords
CarcinogenesisImmune systemCancerAntigenBiologyImmunologyGenetics
MeSH Terms
AnimalsHumansImmunityCellularImmunologic SurveillanceImmunosuppression TherapyNeoplasms
Affiliated Institutions
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Publication Info
- Year
- 1988
- Type
- review
- Volume
- 80
- Issue
- 10
- Pages
- 722-727
- Citations
- 53
- Access
- Closed
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Cite This
M L Kripke
(1988).
Immunoregulation of Carcinogenesis: Past, Present, and Future1.
JNCI Journal of the National Cancer Institute
, 80
(10)
, 722-727.
https://doi.org/10.1093/jnci/80.10.722
Identifiers
- DOI
- 10.1093/jnci/80.10.722
- PMID
- 3290496