Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

Hilary K. Finucane; Yakir Reshef; Verneri Anttila; Kamil Slowikowski; Alexander Gusev; Andrea Byrnes; Steven Gazal; Po‐Ru Loh; Caleb A. Lareau; Noam Shoresh; Giulio Genovese; Arpiar Saunders; Evan Z. Macosko; Samuela Pollack; John R. B. Perry; Jason D. Buenrostro; B Bernstein; Soumya Raychaudhuri; Steven A. McCarroll; Benjamin M. Neale; Alkes L. Price

doi:10.1038/s41588-018-0081-4

Keywords

BiologyGenome-wide association studyHeritabilityLinkage disequilibriumGeneticsGenetic associationComputational biologyGene expression profilingGeneExpression quantitative trait lociGene expressionFalse discovery rateQuantitative trait locusAlleleHaplotypeGenotypeSingle-nucleotide polymorphism

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Publication Info

Year: 2018
Type: article
Volume: 50
Issue: 4
Pages: 621-629
Citations: 1152
Access: Closed

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APA Style

                            
                                
                                    Hilary K. Finucane, 
                                
                                    Yakir Reshef, 
                                
                                    Verneri Anttila
                                
                                et al.
                            
                            (2018). 
                            Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. 
                            Nature Genetics
                            , 50
                            (4)
                            , 621-629.
                            https://doi.org/10.1038/s41588-018-0081-4
                        

Identifiers

DOI: 10.1038/s41588-018-0081-4