Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

2019 Nature Neuroscience 2,604 citations

Keywords

AnhedoniaGenome-wide association studyDepression (economics)Genetic architecturePrefrontal cortexNeuroscienceMoodPsychologyMood disordersMeta-analysisMajor depressive disorderBipolar disorderBiologyGeneticsGenePsychiatryCognitionMedicineSingle-nucleotide polymorphismQuantitative trait locusGenotypeDopamineInternal medicine

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Year
2019
Type
review
Volume
22
Issue
3
Pages
343-352
Citations
2604
Access
Closed

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David M. Howard, Mark J. Adams, Toni‐Kim Clarke et al. (2019). Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nature Neuroscience , 22 (3) , 343-352. https://doi.org/10.1038/s41593-018-0326-7

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DOI
10.1038/s41593-018-0326-7