Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

Ignacio Varela; Patrick Tarpey; Keiran Raine; Dachuan Huang; Choon Kiat Ong; Philip Stephens; Helen Davies; David Jones; Meng Lin; Jon W. Teague; Graham R. Bignell; Adam P. Butler; Juok Cho; Gillian L. Dalgliesh; Danushka Galappaththige; Chris Greenman; Claire Hardy; Mingming Jia; Calli Latimer; King Wai Lau; John L. Marshall; Stuart McLaren; Andrew Menzies; Laura Mudie; Lucy Stebbings; David A. Largaespada; Lodewyk F.A. Wessels; Richard J. Kahnoski; Richard J. Kahnoski; John Anema; David A. Tuveson; Pedro A. Pérez–Mancera; Ville Mustonen; Andrej Fischer; David J. Adams; Alistair G. Rust; Waraporn Chan-on; Chutima Subimerb; Karl Dykema; Kyle Furge; Peter J. Campbell; Bin Tean Teh; Michael R. Stratton; P. Andrew Futreal

doi:10.1038/nature09639

Keywords

BiologyExome sequencingGeneticsGeneHistoneClear cell renal cell carcinomaChromatinExomeCancer researchMutationRenal cell carcinomaMedicine

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Publication Info

Year: 2011
Type: article
Volume: 469
Issue: 7331
Pages: 539-542
Citations: 1255
Access: Closed

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APA Style

                            
                                
                                    Ignacio Varela, 
                                
                                    Patrick Tarpey, 
                                
                                    Keiran Raine
                                
                                et al.
                            
                            (2011). 
                            Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. 
                            Nature
                            , 469
                            (7331)
                            , 539-542.
                            https://doi.org/10.1038/nature09639
                        

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DOI: 10.1038/nature09639