Effects of perfusion pressure on tissue perfusion in septic shock

Abstract

Increasing the MAP from 65 mm Hg to 85 mm Hg with norepinephrine does not significantly affect systemic oxygen metabolism, skin microcirculatory blood flow, urine output, or splanchnic perfusion.

Keywords

MedicineSeptic shockCardiac indexMean arterial pressureCardiac outputPerfusionVascular resistancePulmonary wedge pressureIntensive careNorepinephrineAnesthesiaShock (circulatory)HemodynamicsBlood pressureCardiologyInternal medicineHeart rateSepsis

Affiliated Institutions

Related Publications

Increasing mean arterial pressure in patients with septic shock: Effects on oxygen variables and renal function*

Aurélie Bourgoin , Marc Léone , Anne Delmas +3 more

Increasing mean arterial pressure from 65 to 85 mm Hg with norepinephrine neither affects metabolic variables nor improves renal function.

2005 Critical Care Medicine 327 citations

High versus Low Blood-Pressure Target in Patients with Septic Shock

Olivier Lesieur , Jean‐Damien Ricard , F. Hervé +28 more

Targeting a mean arterial pressure of 80 to 85 mm Hg, as compared with 65 to 70 mm Hg, in patients with septic shock undergoing resuscitation did not result in significant diffe...

2014 New England Journal of Medicine 1140 citations

The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects*

Daniel De Backer , Jacques Créteur , Marc‐Jacques Dubois +4 more

The administration of 5 mug/kg.min dobutamine can improve but not restore capillary perfusion in patients with septic shock. These changes are independent of changes in systemic...

2006 Critical Care Medicine 483 citations

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

R. Phillip Dellinger , Mitchell M. Levy , Jean Carlet +21 more

Erratum in Crit Care Med. 2008 Apr;36(4):1394-6. \nAbstract\nOBJECTIVE: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, ...

2008 Archivio istituzionale della ricerca ... 3903 citations

The Preoperative and Intraoperative Hemodynamic Predictors of Postoperative Myocardial Infarction or Ischemia in Patients Undergoing Noncardiac Surgery

Mary E. Charlson , C. Ronald MacKenzie , Jeffrey P. Gold +4 more

Among hypertensive and diabetic patients undergoing elective noncardiac surgery, preoperative status and intraoperative changes in mean arterial pressure (MAP) were evaluated as...

1989 Annals of Surgery 117 citations

Publication Info

Year: 2000
Type: article
Volume: 28
Issue: 8
Pages: 2729-2732
Citations: 601
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Effects of perfusion pressure on tissue perfusion in septic shock

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

601

OpenAlex

Cite This

APA Style

                            
                                
                                    Didier Ledoux, 
                                
                                    Mark E. Astiz, 
                                
                                    Charles Carpati
                                
                                et al.
                            
                            (2000). 
                            Effects of perfusion pressure on tissue perfusion in septic shock. 
                            Critical Care Medicine
                            , 28
                            (8)
                            , 2729-2732.
                            https://doi.org/10.1097/00003246-200008000-00007
                        

Identifiers

DOI: 10.1097/00003246-200008000-00007