High versus Low Blood-Pressure Target in Patients with Septic Shock

Abstract

Targeting a mean arterial pressure of 80 to 85 mm Hg, as compared with 65 to 70 mm Hg, in patients with septic shock undergoing resuscitation did not result in significant differences in mortality at either 28 or 90 days. (Funded by the French Ministry of Health; SEPSISPAM ClinicalTrials.gov number, NCT01149278.).

Keywords

MedicineSeptic shockHazard ratioResuscitationBlood pressureConfidence intervalSurviving Sepsis CampaignSepsisInternal medicineIncidence (geometry)Atrial fibrillationShock (circulatory)Clinical endpointAdverse effectCardiologySurgeryRandomized controlled trialSevere sepsis

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Publication Info

Year: 2014
Type: article
Volume: 370
Issue: 17
Pages: 1583-1593
Citations: 1140
Access: Closed

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APA Style

                            
                                
                                    Olivier Lesieur, 
                                
                                    Jean‐Damien Ricard, 
                                
                                    F. Hervé
                                
                                et al.
                            
                            (2014). 
                            High versus Low Blood-Pressure Target in Patients with Septic Shock. 
                            New England Journal of Medicine
                            , 370
                            (17)
                            , 1583-1593.
                            https://doi.org/10.1056/nejmoa1312173
                        

Identifiers

DOI: 10.1056/nejmoa1312173