Abstract

This book is a self-contained introduction to the theory of atomic motion in proteins and nucleic acids. An understanding of such motion is essential because it plays a crucially important role in biological activity. The authors, both of whom are well known for their work in this field, describe in detail the major theoretical methods that are likely to be useful in the computer-aided design of drugs, enzymes and other molecules. A variety of theoretical and experimental studies is described and these are critically analyzed to provide a comprehensive picture of dynamic aspects of biomolecular structure and function. The book will be of interest to graduate students and research workers in structural biochemistry (X-ray diffraction and NMR), theoretical chemistry (liquids and polymers), biophysics, enzymology, molecular biology, pharmaceutical chemistry, genetic engineering and biotechnology.

Keywords

Nucleic acidChemistryFunction (biology)NanotechnologyGraduate studentsVariety (cybernetics)Computational biologyBiochemical engineeringBiochemistryComputer scienceBiologyMaterials scienceEngineeringGeneticsMedicine

Affiliated Institutions

Related Publications

Matrix Analysis

In this book the authors present classical and recent results for matrix analysis that have proved to be important to applied mathematics. Facts about matrices, beyond those fou...

1985 Cambridge University Press eBooks 9982 citations

Publication Info

Year
1987
Type
book
Citations
1244
Access
Closed

External Links

Social Impact

Altmetric

Social media, news, blog, policy document mentions

Citation Metrics

1244
OpenAlex

Cite This

J. Andrew McCammon, Stephen C. Harvey (1987). Dynamics of Proteins and Nucleic Acids. Cambridge University Press eBooks . https://doi.org/10.1017/cbo9781139167864

Identifiers

DOI
10.1017/cbo9781139167864