Droplet microfluidics for single-cell analysis: From improved cell encapsulation and sorting technologies to innovative applications

Shuwei Song; Jiaran Lu; Xinyue Jiang; Jiaqi Zhao; Xinran Xiang; Yuting Shang

doi:10.1016/j.biotechadv.2025.108777

Affiliated Institutions

Related Publications

On-Chip Single-Copy Real-Time Reverse-Transcription PCR in Isolated Picoliter Droplets

N. Reginald Beer , Elizabeth K. Wheeler , Lorenna Lee-Houghton +7 more

The first lab-on-chip system for picoliter droplet generation and RNA isolation, followed by reverse transcription, and PCR amplification with real-time fluorescence detection i...

2008 Analytical Chemistry 209 citations

Microfluidic devices fabricated in Poly(dimethylsiloxane) for biological studies

Samuel K. Sia , George M. Whitesides

Abstract This review describes microfluidic systems in poly(dimethylsiloxane) (PDMS) for biological studies. Properties of PDMS that make it a suitable platform for miniaturized...

2003 Electrophoresis 1697 citations

Microfluidic Device for Single-Cell Analysis

Aaron R. Wheeler , William Throndset , Rebecca J. Whelan +6 more

We have developed a novel microfluidic device constructed from poly(dimethylsiloxane) using multilayer soft lithography technology for the analysis of single cells. The microflu...

2003 Analytical Chemistry 595 citations

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

The Tabula Muris Consortium , Overall coordination , Logistical coordination +3 more

Here we present a compendium of single-cell transcriptomic data from the model organism Mus musculus that comprises more than 100,000 cells from 20 organs and tissues. These dat...

2018 Nature 2962 citations

A microfluidic device to confine a single cardiac myocyte in a sub-nanoliter volume on planar microelectrodes for extracellular potential recordings

Andreas A. Werdich , Eduardo A. Lima , B. Ivanov +4 more

A hybrid chip is described which combines a microfluidic network fabricated in a silicone elastomer (PDMS) with planar microelectrodes. It was used to measure extracellular pote...

2004 Lab on a Chip 106 citations

Publication Info

Year: 2025
Type: review
Volume: 87
Pages: 108777-108777
Citations: 0
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Droplet microfluidics for single-cell analysis: From improved cell encapsulation and sorting technologies to innovative applications

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                    Shuwei Song, 
                                
                                    Jiaran Lu, 
                                
                                    Xinyue Jiang
                                
                                et al.
                            
                            (2025). 
                            Droplet microfluidics for single-cell analysis: From improved cell encapsulation and sorting technologies to innovative applications. 
                            Biotechnology Advances
                            , 87
                            
                            , 108777-108777.
                            https://doi.org/10.1016/j.biotechadv.2025.108777

Identifiers

DOI: 10.1016/j.biotechadv.2025.108777