Abstract
Diabetes and a low high-density lipoprotein cholesterol level are associated with each other and with a higher coronary heart disease risk in women. Moreover, both are strongly associated with obesity. These findings are reported from the Framington Study, in which persons aged 49 to 82 were characterized, after overnight fast, for blood lipids by the method of Fredrickson and Levy and then followed for the subsequent development of coronary heart disease. Low-density lipoprotein cholesterol was also associated with coronary heart disease risk in women, but fasting triglycerides were not associated with risk after allowing for the association with high-density lipoprotein cholesterol and diabetes. A low high-density lipoprotein cholesterol in the presence of diabetes appeared to raise the coronary heart disease risk in women relative to that of men.
Keywords
MedicineDiabetes mellitusInternal medicineCholesterolObesityCardiologyHigh-density lipoproteinRisk factorLipoproteinFramingham Risk ScoreBlood lipidsDiseaseEndocrinologyCoronary heart disease
Related Publications
Nonalcoholic Fatty Liver, Steatohepatitis, and the Metabolic Syndrome
Nonalcoholic fatty liver disease (NAFLD) has been associated with the insulin–resistance syndrome, at present defined as the metabolic syndrome, whose limits were recently set. ...
Impaired Glucose Tolerance in the U. S. Population
Impaired glucose tolerance (IGT) constitutes two-thirds of all glucose intolerance in the United States and is a major risk factor for diabetes. Despite these findings, the clin...
Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease
Most evidence about the effects of blood pressure on the risks of cardiovascular disease derives from two principal sources: prospective non-randomised observational studies of ...
Prevalence and risk factors for non‐alcoholic fatty liver disease among adults in an urban Sri Lankan population
Abstract Background and Aims: Non‐alcoholic fatty liver disease (NAFLD) is an emerging problem in the Asia–Pacific region. However, its prevalence and risk factors in Asian (esp...
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
1. The most important way to prevent atherosclerotic vascular disease, heart failure, and atrial fibrillation is to promote a healthy lifestyle throughout life. 2. A team-based ...
Publication Info
- Year
- 1977
- Type
- article
- Volume
- 87
- Issue
- 4
- Pages
- 393-397
- Citations
- 371
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
371
OpenAlex
Cite This
Tavia Gordon
(1977).
Diabetes, Blood Lipids, and the Role of Obesity in Coronary Heart Disease Risk for Women.
Annals of Internal Medicine
, 87
(4)
, 393-397.
https://doi.org/10.7326/0003-4819-87-4-393
Identifiers
- DOI
- 10.7326/0003-4819-87-4-393