Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

Stephen Haskill; Amer A. Beg; S. Mark Tompkins; John S Morris; Andrew D. Yurochko; Adam Sampson-Johannes; Krishna Mondal; Peter Ralph; Albert S. Baldwin

doi:10.1016/0092-8674(91)90022-q

Keywords

BiologyAnkyrin repeatMolecular biologyGeneComplementary DNATandem repeatAnkyrinPhosphorylationDNACell biologyGeneticsGenome

Affiliated Institutions

University of North Carolina at Chapel Hill US

Related Publications

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

Sankar Ghosh , Michael J. May , Elizabeth B. Kopp

▪ Abstract The transcription factor NF-κB, more than a decade after its discovery, remains an exciting and active area of study. The involvement of NF-κB in the expression of nu...

1998 Annual Review of Immunology 5154 citations

The IKK Complex, a Central Regulator of NF- B Activation

Alain Israël

The IKK kinase complex is the core element of the NF-kappaB cascade. It is essentially made of two kinases (IKKalpha and IKKbeta) and a regulatory subunit, NEMO/IKKgamma. Additi...

2009 Cold Spring Harbor Perspectives in Bi... 801 citations

TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells

Brian Wong , Jaerang Rho , Joseph R. Arron +9 more

A novel member of the tumor necrosis factor (TNF) cytokine family, designated TRANCE, was cloned during a search for apoptosis-regulatory genes using a somatic cell genetic appr...

1997 Journal of Biological Chemistry 1055 citations

NF-κB: a key role in inflammatory diseases

Paul P. Tak , Gary S. Firestein

NF-κB in defense and diseaseActivation of the NF-κB/Rel transcription family, by nuclear translocation of cytoplasmic complexes, plays a central role in inflammation through its...

2001 Journal of Clinical Investigation 3811 citations

The NF- B Family of Transcription Factors and Its Regulation

Andrea Oeckinghaus , Sankar Ghosh

Nuclear factor-kappaB (NF-kappaB) consists of a family of transcription factors that play critical roles in inflammation, immunity, cell proliferation, differentiation, and surv...

2009 Cold Spring Harbor Perspectives in Bi... 2706 citations

Publication Info

Year: 1991
Type: article
Volume: 65
Issue: 7
Pages: 1281-1289
Citations: 726
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

726

OpenAlex

Cite This

APA Style

                            
                                
                                    Stephen Haskill, 
                                
                                    Amer A. Beg, 
                                
                                    S. Mark Tompkins
                                
                                et al.
                            
                            (1991). 
                            Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity. 
                            Cell
                            , 65
                            (7)
                            , 1281-1289.
                            https://doi.org/10.1016/0092-8674(91)90022-q
                        

Identifiers

DOI: 10.1016/0092-8674(91)90022-q