Cancer as an evolutionary and ecological process

Keywords

BiologyCancerMicrocosmEcologyEvolutionary ecologyProcess (computing)Evolutionary biologyImmune systemHost (biology)ImmunologyComputer scienceGenetics

Affiliated Institutions

Related Publications

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

Erick Riquelme , Yu Zhang , Liangliang Zhang +28 more

Most patients diagnosed with resected pancreatic adenocarcinoma (PDAC) survive less than 5 years, but a minor subset survives longer. Here, we dissect the role of the tumor micr...

2019 Cell 1429 citations

The tumor microenvironment

Nicole Anderson , M. Celeste Simon

A tumor is not simply a group of cancer cells, but rather a heterogeneous collection of infiltrating and resident host cells, secreted factors and extracellular matrix. Tumor ce...

2020 Current Biology 2339 citations

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

Ethan Cerami , Jianjiong Gao , Uğur Doğrusöz +12 more

Abstract The cBio Cancer Genomics Portal (http://cbioportal.org) is an open-access resource for interactive exploration of multidimensional cancer genomics data sets, currently ...

2012 Cancer Discovery 17518 citations

Hallmarks of response, resistance, and toxicity to immune checkpoint blockade

Golnaz Morad , Beth A. Helmink , Padmanee Sharma +1 more

Unprecedented advances have been made in cancer treatment with the use of immune checkpoint blockade (ICB). However, responses are limited to a subset of patients, and immune-re...

2021 Cell 1455 citations

The Three Es of Cancer Immunoediting

Gavin P. Dunn , Lloyd J. Old , Robert D. Schreiber

After a century of controversy, the notion that the immune system regulates cancer development is experiencing a new resurgence. An overwhelming amount of data from animal model...

2004 Annual Review of Immunology 2939 citations

Publication Info

Year: 2006
Type: review
Volume: 6
Issue: 12
Pages: 924-935
Citations: 1691
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Cancer as an evolutionary and ecological process

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1691

OpenAlex

Cite This

APA Style

                            
                                
                                    Lauren M.F. Merlo, 
                                
                                    John W. Pepper, 
                                
                                    Brian J. Reid
                                
                                et al.
                            
                            (2006). 
                            Cancer as an evolutionary and ecological process. 
                            Nature reviews. Cancer
                            , 6
                            (12)
                            , 924-935.
                            https://doi.org/10.1038/nrc2013
                        

Identifiers

DOI: 10.1038/nrc2013