Biosynthese eines Enzyms. Information, Induktion, Repression

Abstract

Abstract Die genetische und biochemische Untersuchung des Systems, das bei Escherichia coli für die Synthese der β‐Galactosidase verantwortlich ist, ergab, daß die Fähigkeit zur Enzymsynthese von einem Gen bestimmt wird, das offenbar die gesamte Information über die Struktur des Proteinmoleküls enthält. Ein zweites Gen, dem ersten unmittelbar benachbart, aber von ihm funktionell unabhängig, steuert die Bildung eines Repressors, dessen Aufgabe es ist, die Aktivität des galactosidase‐synthetisierenden Systems zu hemmen. Extrazelluläre Induktoren, welche die Synthese des Enzyms stimulieren, wirken als Antagonisten des intrazellulären Repressors.

Keywords

ChemistryMolecular biologyPhilosophyBiology

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Publication Info

Year: 1959
Type: article
Volume: 71
Issue: 22
Pages: 685-691
Citations: 38
Access: Closed

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APA Style

                            
                                    Jacques Monod
                                
                            (1959). 
                            Biosynthese eines Enzyms. Information, Induktion, Repression. 
                            Angewandte Chemie
                            , 71
                            (22)
                            , 685-691.
                            https://doi.org/10.1002/ange.19590712202

Identifiers

DOI: 10.1002/ange.19590712202