Biomolecular Recognition Based on Single Gold Nanoparticle Light Scattering

G. Raschke; Stefan Kowarik; T. Franzl; Carsten Sönnichsen; Thomas A. Klar; Jochen Feldmann; Alfons Nichtl; K. Kürzinger

doi:10.1021/nl034223+

Abstract

A method for biomolecular recognition is reported using light scattering of a single gold nanoparticle functionalized with biotin. Addition of streptavidin and subsequent specific binding events alter the dielectric environment of the nanoparticle, resulting in a spectral shift of the particle plasmon resonance. As we use single nanoparticles showing a homogeneous scattering spectrum, spectral shifts as small as 2 meV can be detected.

Keywords

NanoparticleNanotechnologyColloidal goldMaterials scienceLight scatteringScatteringChemistryOpticsPhysics

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Publication Info

Year: 2003
Type: article
Volume: 3
Issue: 7
Pages: 935-938
Citations: 703
Access: Closed

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APA Style

                            
                                
                                    G. Raschke, 
                                
                                    Stefan Kowarik, 
                                
                                    T. Franzl
                                
                                et al.
                            
                            (2003). 
                            Biomolecular Recognition Based on Single Gold Nanoparticle Light Scattering. 
                            Nano Letters
                            , 3
                            (7)
                            , 935-938.
                            https://doi.org/10.1021/nl034223+
                        

Identifiers

DOI: 10.1021/nl034223+