Abstract

Computational evolutionary biology, statistical phylogenetics and coalescent-based population genetics are becoming increasingly central to the analysis and understanding of molecular sequence data. We present the Bayesian Evolutionary Analysis by Sampling Trees (BEAST) software package version 1.7, which implements a family of Markov chain Monte Carlo (MCMC) algorithms for Bayesian phylogenetic inference, divergence time dating, coalescent analysis, phylogeography and related molecular evolutionary analyses. This package includes an enhanced graphical user interface program called Bayesian Evolutionary Analysis Utility (BEAUti) that enables access to advanced models for molecular sequence and phenotypic trait evolution that were previously available to developers only. The package also provides new tools for visualizing and summarizing multispecies coalescent and phylogeographic analyses. BEAUti and BEAST 1.7 are open source under the GNU lesser general public license and available at http://beast-mcmc.googlecode.com and http://beast.bio.ed.ac.uk.

Keywords

Coalescent theoryMarkov chain Monte CarloBiologyEvolutionary biologyPhylogenetic treeBayesian probabilityPhylogeneticsPhylogeographyMost recent common ancestorComputer scienceArtificial intelligenceGenetics

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Year
2012
Type
article
Volume
29
Issue
8
Pages
1969-1973
Citations
10198
Access
Closed

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Alexei J. Drummond, Marc A. Suchard, Dong Xie et al. (2012). Bayesian Phylogenetics with BEAUti and the BEAST 1.7. Molecular Biology and Evolution , 29 (8) , 1969-1973. https://doi.org/10.1093/molbev/mss075

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DOI
10.1093/molbev/mss075