Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma

2020 New England Journal of Medicine 1,374 citations

Abstract

Maintenance avelumab plus best supportive care significantly prolonged overall survival, as compared with best supportive care alone, among patients with urothelial cancer who had disease that had not progressed with first-line chemotherapy. (Funded by Pfizer and Merck [Darmstadt, Germany]; JAVELIN Bladder 100 ClinicalTrials.gov number, NCT02603432.).

Keywords

AvelumabUrothelial carcinomaMetastatic Urothelial CarcinomaChemotherapyOncologyMedicineInternal medicineCarcinomaStandard of careImmunotherapyCancerBladder cancerPembrolizumab

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Publication Info

Year
2020
Type
article
Volume
383
Issue
13
Pages
1218-1230
Citations
1374
Access
Closed

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Thomas Powles, Se Hoon Park, Éric Voog et al. (2020). Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma. New England Journal of Medicine , 383 (13) , 1218-1230. https://doi.org/10.1056/nejmoa2002788

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DOI
10.1056/nejmoa2002788