Abstract

There is no clear evidence that atypical antipsychotics are more effective or are better tolerated than conventional antipsychotics. Conventional antipsychotics should usually be used in the initial treatment of an episode of schizophrenia unless the patient has previously not responded to these drugs or has unacceptable extrapyramidal side effects.

Keywords

AmisulprideOlanzapineQuetiapineRisperidoneSertindoleTolerabilityClozapineAntipsychoticExtrapyramidal symptomsAtypical antipsychoticMedicinePsychiatryHaloperidolTypical antipsychoticPsychologySchizophrenia (object-oriented programming)Internal medicineAdverse effectDopamine

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Publication Info

Year
2000
Type
review
Volume
321
Issue
7273
Pages
1371-1376
Citations
1065
Access
Closed

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John Geddes, Nick Freemantle, Paul J. Harrison et al. (2000). Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis. BMJ , 321 (7273) , 1371-1376. https://doi.org/10.1136/bmj.321.7273.1371

Identifiers

DOI
10.1136/bmj.321.7273.1371