Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

2018 New England Journal of Medicine 3,592 citations

Abstract

The addition of atezolizumab to bevacizumab plus chemotherapy significantly improved progression-free survival and overall survival among patients with metastatic nonsquamous NSCLC, regardless of PD-L1 expression and EGFR or ALK genetic alteration status. (Funded by F. Hoffmann-La Roche/Genentech; IMpower150 ClinicalTrials.gov number, NCT02366143 .).

Keywords

AtezolizumabOncologyMedicineInternal medicineCancerImmunotherapyNivolumab

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Publication Info

Year
2018
Type
article
Volume
378
Issue
24
Pages
2288-2301
Citations
3592
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Mark A. Socinski, Robert M. Jotte, Federico Cappuzzo et al. (2018). Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC. New England Journal of Medicine , 378 (24) , 2288-2301. https://doi.org/10.1056/nejmoa1716948

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DOI
10.1056/nejmoa1716948