Assessing Clinical and Functional Outcomes in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Schizophrenia Trial

M S Swartz; Diana O. Perkins; T. Scott Stroup; Joseph P. McEvoy; Jennifer Nieri; Daniel Haak

doi:10.1093/oxfordjournals.schbul.a006989

Abstract

Schizophrenia is a symptomatically heterogeneous disorder characterized by the presence of positive and negative symptoms, and variable impairment in community functioning. Given the diversity of symptom presentations and functioning associated with schizophrenia, one of the key challenges facing the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial was the selection of efficient assessment measures appropriate to a community-based effectiveness trial. This article describes the rationale for the measurement approach adopted for the trial, provides a brief overview of the selected measures, and describes the process of training assessment raters for a large and geographically dispersed study group.

Keywords

Schizophrenia (object-oriented programming)AntipsychoticClinical trialIntervention (counseling)PsychiatryRandomized controlled trialPsychologyMedicineClinical psychologyInternal medicine

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Publication Info

Year: 2003
Type: article
Volume: 29
Issue: 1
Pages: 33-43
Citations: 109
Access: Closed

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APA Style

                            
                                
                                    M S Swartz, 
                                
                                    Diana O. Perkins, 
                                
                                    T. Scott Stroup
                                
                                et al.
                            
                            (2003). 
                            Assessing Clinical and Functional Outcomes in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Schizophrenia Trial. 
                            Schizophrenia Bulletin
                            , 29
                            (1)
                            , 33-43.
                            https://doi.org/10.1093/oxfordjournals.schbul.a006989
                        

Identifiers

DOI: 10.1093/oxfordjournals.schbul.a006989