Keywords
WeightingBiologyBasis (linear algebra)Similarity (geometry)Permutation (music)Sequence alignmentSimple (philosophy)Structural alignmentA priori and a posterioriMathematicsGeneticsCombinatoricsComputational biologyAlgorithmComputer sciencePeptide sequenceArtificial intelligence
Affiliated Institutions
Related Publications
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved for the alignment of divergent protein sequences. Firstly, individu...
Profile analysis: detection of distantly related proteins.
Profile analysis is a method for detecting distantly related proteins by sequence comparison. The basis for comparison is not only the customary Dayhoff mutational-distance matr...
Automatic generation of primary sequence patterns from sets of related protein sequences.
We have developed a computer algorithm that can extract the pattern of conserved primary sequence elements common to all members of a homologous protein family. The method invol...
Database of homology‐derived protein structures and the structural meaning of sequence alignment
Abstract The database of known protein three‐dimensional structures can be significantly increased by the use of sequence homology, based on the following observations. (1) The ...
Fast protein fold recognition via sequence to structure alignment and contact capacity potentials.
We propose new empirical scoring potentials and associated alignment procedures for optimally aligning protein sequences to protein structures. The method has two main applicati...
Publication Info
- Year
- 1985
- Type
- article
- Volume
- 21
- Issue
- 2
- Pages
- 112-125
- Citations
- 395
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
395
OpenAlex
Cite This
Da-Fei Feng,
Mark S. Johnson,
Russell F. Doolittle
(1985).
Aligning amino acid sequences: Comparison of commonly used methods.
Journal of Molecular Evolution
, 21
(2)
, 112-125.
https://doi.org/10.1007/bf02100085
Identifiers
- DOI
- 10.1007/bf02100085