A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less

1997 New England Journal of Medicine 2,664 citations

Abstract

Treatment with indinavir, zidovudine, and lamivudine as compared with zidovudine and lamivudine alone significantly slows the progression of HIV-1 disease in patients with 200 CD4 cells or fewer per cubic millimeter and prior exposure to zidovudine.

Keywords

IndinavirLamivudineZidovudineMedicineHazard ratioVirologyStavudineInternal medicineRegimenProtease inhibitor (pharmacology)GastroenterologySidaConfidence intervalImmunologyViral loadViral diseaseVirus

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Publication Info

Year
1997
Type
article
Volume
337
Issue
11
Pages
725-733
Citations
2664
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Scott M. Hammer, Kathleen Squires, Michael D. Hughes et al. (1997). A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less. New England Journal of Medicine , 337 (11) , 725-733. https://doi.org/10.1056/nejm199709113371101

Identifiers

DOI
10.1056/nejm199709113371101