University of South Florida St. Petersburg

Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency

Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily share an intracytoplasmic Toll–IL-1 receptor (TIR) domain, which mediates recruitment of t...

<i>BRCA1</i> and <i>BRCA2</i> mutations account for a large proportion of ovarian carcinoma cases

Abstract BACKGROUND It is believed that BRCA1 and BRCA2 germline mutations account for the majority of hereditary ovarian carcinomas; however, to the authors' knowledge, there a...

Climate Response to Orbital Forcing Across the Oligocene-Miocene Boundary

Spectral analyses of an uninterrupted 5.5-million-year (My)–long chronology of late Oligocene–early Miocene climate and ocean carbon chemistry from two deep-sea cores recovered ...

Orbitally paced climate oscillations across the Oligocene/Miocene boundary