Sun Yat-sen University Cancer Center

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma is characterised by distinct geographical distribution and is particularly prevalent in east and southeast Asia. Epidemiological trends in the past deca...

Current cancer situation in China: good or bad news from the 2018 Global Cancer Statistics?

Abstract Cancer is the leading cause of death in China and depicting the cancer pattern of China would provide basic knowhows on how to tackle it more effectively. In this study...

Circular RNA: metabolism, functions and interactions with proteins

Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules that are ubiquitous across species ranging from viruses to mammals. Important advances have been ma...

A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells

m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

Roles of IFN-γ in tumor progression and regression: a review

Integrated Multiomics Analysis and Experimental Validation Identify ITPRIPL1 as an Immunoregulatory and Prognostic Biomarker in Gastric Adenocarcinoma

ABSTRACT Background Inositol 1,4,5‐trisphosphate receptor‐interacting protein‐like 1 (ITPRIPL1) has been identified as an inhibitory ligand of CD3ε, but its role in stomach aden...

Immunotherapy Inhibits Tumor Cholesterol Synthesis via the IFN-γ-ΙRF1-SREBF2 Axis

Abstract Tumor cells employ metabolic mechanisms to limit antitumor immunity and promote resistance to immunotherapy. However, how immunotherapy modulates tumor metabolism remai...