Nippon Medical School

A cross-population atlas of genetic associations for 220 human phenotypes

Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease

Among patients with ILD associated with systemic sclerosis, the annual rate of decline in FVC was lower with nintedanib than with placebo; no clinical benefit of nintedanib was ...

Diabetes Mellitus May Increase Risk for Idiopathic Pulmonary Fibrosisa

Elevated Troponin T Levels and Lesion Characteristics in Non–ST-Elevation Acute Coronary Syndromes

Background— Elevated troponin T levels in non–ST-elevation acute coronary syndromes (NSTE-ACS) have been shown to predict an adverse outcome. Furthermore, it has been reported t...

Sensitive assay of RNA interference in <i>Drosophila</i> and Chinese hamster cultured cells using firefly luciferase gene as target

A sensitive cellular assay system for RNA interference was developed using the firefly luciferase gene as target. RNA interference was noted not only in Drosophila cultured cell...

Systematic search for zinc‐binding proteins in <i>Escherichia coli</i>

A systematic search for Escherichia coli proteins with the zinc‐binding activity was performed using the assay of radioactive Zn(II) binding to total E. coli proteins fractionat...