National Foundation for Cancer Research

New Perspectives in Cell Adhesion: RGD and Integrins

Rapid progress has been made in the understanding of the molecular interactions that result in cell adhesion. Many adhesive proteins present in extracellular matrices and in the...

Human ICE/CED-3 Protease Nomenclature

Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices

Abstract Artificial Intelligence (AI) has long promised to increase healthcare affordability, quality and accessibility but FDA, until recently, had never authorized an autonomo...

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA

When the mammalian proto-oncogene bcl-2 is overexpressed it can protect various types of cells both from normal and from experimentally induced apoptosis, but the molecular mech...

Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria

Apoptotic cell death involves a ritual series of morphological changes, presumably reflecting a conserved molecular pathway. We now report that the nuclear events typical of apo...

Assembly and Stability of the Tobacco Mosaic Virus Particle

Neural apoptosis

Abstract Apoptosis is a mode of cell death in which the cell plays an active role in its own demise. The study of neural apoptosis, the identification of genes controlling apopt...

A Novel Thyroid Hormone Receptor Encoded by a cDNA Clone from a Human Testis Library

The c- erb A gene belongs to a multigene family that encodes transcriptional regulatory proteins including the v- erb A oncogene product, steroid hormone receptors, and the vita...

Regulation of the immune response by subclasses of T lymphocytes. II. The effect of adult thymectomy upon humoral and cellular responses in mice

Abstract The immunologic consequences resulting from thymectomy in adult lifewere investigated. Primary humoral responses were not diminished shortlyafter adult thymectomy, as j...

TUMORIGENIC ACTIVITY OF TISSUE CELL CULTURES*