MRC Centre for Reproductive Health

Targeting macrophages: therapeutic approaches in cancer

Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?

Microglia states and nomenclature: A field at its crossroads

Microglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2....

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available. To obtain a be...

Brain charts for the human lifespan

Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist t...

The consequences of obesity and excess weight gain in pregnancy

The prevalence of obesity in pregnancy is rising exponentially; about 15–20% of pregnant women now enter pregnancy with a BMI which would define them as obese. This paper provid...