Lundbeck (Denmark)

Biological insights from 108 schizophrenia-associated genetic loci

Common variants at VRK2 and TCF4 conferring risk of schizophrenia

Common sequence variants have recently joined rare structural polymorphisms as genetic factors with strong evidence for association with schizophrenia. Here we extend our previo...

Efficacy of small‐molecule glycogen synthase kinase‐3 inhibitors in the postnatal rat model of tau hyperphosphorylation

Background and purpose: Glycogen synthase kinase‐3 (GSK‐3) affects neuropathological events associated with Alzheimeŕs disease (AD) such as hyperphosphorylation of the protein, ...

Cystatin C reduces the<i>in vitro</i>formation of soluble Aβ1‐42 oligomers and protofibrils

There are an increasing number of genetic and neuropathological observations to suggest that cystatin C, an extracellular protein produced by all nucleated cells, might play a r...