Athena Group (United States)

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

The amyloid β peptide (AβP) is a small fragment of the much larger, broadly distributed amyloid precursor protein (APP). Abundant AβP deposition in the brains of patients with A...

Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage, Dutch Type

An amyloid protein that precipitates in the cerebral vessel walls of Dutch patients with hereditary cerebral hemorrhage with amyloidosis is similar to the amyloid protein in ves...

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells

Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis

Recent genetic and biochemical studies have implicated cysteine-dependent aspartate-directed proteases (caspases) in the active phase of apoptosis. In the present study, three c...