W. Taylor Kimberly - Researcher Profile

Publications

3 shown

Recommendations for the Management of Cerebral and Cerebellar Infarction With Swelling

Eelco F. M. Wijdicks , Kevin N. Sheth , Bob S. Carter +7 more

Background and Purpose— There are uncertainties surrounding the optimal management of patients with brain swelling after an ischemic stroke. Guidelines are needed on how to mana...

2014 Stroke 495 citations

Aspartate Mutations in Presenilin and γ‐Secretase Inhibitors Both Impair Notch1 Proteolysis and Nuclear Translocation with Relative Preservation of Notch1 Signaling

Oksana Berezovska , Christine Jack , Pamela J. McLean +8 more

It has been hypothesized that a presenilin 1 (PS1)‐related enzymatic activity is responsible for proteolytic cleavage of the C‐terminal intracellular protein of Notch1, in addit...

2000 Journal of Neurochemistry 119 citations