Toby Lawrence

“Re-educating” tumor-associated macrophages by targeting NF-κB

The nuclear factor κB (NF-κB) signaling pathway is important in cancer-related inflammation and malignant progression. Here, we describe a new role for NF-κB in cancer in mainta...

The Nuclear Factor NF- B Pathway in Inflammation

The nuclear factor NF-kappaB pathway has long been considered a prototypical proinflammatory signaling pathway, largely based on the role of NF-kappaB in the expression of proin...

Chronic inflammation: a failure of resolution?

Summary Inflammation has evolved as a protective response to insult or injury, it's a primordial response that eliminates or neutralises foreign organisms or material, the resol...

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

Transcriptional regulation of macrophage polarization: enabling diversity with identity