Supplementary Figure S6 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Loss of GRAMD1B promotes tumor cell invasion in human melanoma cells</p>
Publications
16 shownA zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
Visualizing the beginnings of melanoma In cancer biology, a tumor begins from a single cell within a group of precancerous cells that share genetic mutations. Kaufman et al. use...
Supplementary Figure S8 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Cholesterol overload activates AP-1 via ERK signaling to mediate invasion upon GRAMD1B loss in melanoma.</p>
Supplementary Figure S5 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supp. Fig. S5 shows that GRAMD1B is a metastasis suppressor in human melanoma</p>
Supp Table S2 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supplementary Table S2. David GO analysis of AVAST-M signature</p>
Supplementary Figure S7 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Loss of GRAMD1B suppresses de novo cholesterol synthesis in melanoma cells.</p>
Supplementary Figure S2 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>CRISPR Sequencing of MAS2X tumors.</p>
Supp Table S5 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supplementary Table S5. Normalized Counts of transcripts in GRAMD1B KO and NT cells.</p>
Supp Table S4 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supp Table S4 has a list of antibodies and other resources</p>
Supplementary Figure S3 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Validation of gramd1b depletion in zebrafish cells and tumors.</p>
Supplementary Figure S1 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>The AVAST-M trial identifies a signature predictive of metastatic relapse</p>
Supp Table S3 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supp Table S3 has a List of Oligonucleotides Sequences</p>
Supp Table S1 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supplementary Table S1. List of genes predictive of metastasis from AVAST-M trial. </p>
Supplementary Figure S4 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>An in vivo screen identifies metastasis suppressors in melanoma.</p>
Supp Table S6 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supp Table S6 Differentially Expressed Genes</p>
Supp Table S7 from Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
<p>Supp Table S7: GSEA Analysis</p>
Frequent Co-Authors
Researcher Info
- h-index
- 1
- Publications
- 16
- Citations
- 413
- Institution
- Cornell University
External Links
Identifiers
- ORCID
- 0000-0001-9099-9169
Impact Metrics
h-index
1
h-index: Number of publications with at least h citations each.