On the role of helper lipids in lipid nanoparticle formulations of siRNA
In empty LNP formulations, DSPC–cholesterol resides in outer layers, whereas in loaded systems some of the DSPC–cholesterol is internalized together with siRNA.
Publications
4 shownMicrofluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems
Previous work has shown that lipid nanoparticles (LNP) composed of an ionizable cationic lipid, a poly(ethylene glycol) (PEG) lipid, distearoylphosphatidylcholine (DSPC), choles...
Frequent Co-Authors
Researcher Info
- h-index
- 4
- Publications
- 4
- Citations
- 3,213
- Institution
- NanoMedicines Innovation Network
External Links
Identifiers
- ORCID
- 0000-0001-9586-2508
Impact Metrics
h-index
4
h-index: Number of publications with at least h citations each.