Peter Peduzzi

Importance of events per independent variable in proportional hazards regression analysis II. Accuracy and precision of regression estimates

The analytical effect of the number of events per variable (EPV) in a proportional hazards regression analysis was evaluated using Monte Carlo simulation techniques for data fro...

Importance of events per independent variable in proportional hazards analysis I. Background, goals, and general strategy

Multivariable methods of analysis can yield problematic results if methodological guidelines and mathematical assumptions are ignored. A problem arising from a too-small ratio o...

Section 2 Design and baseline characteristics

Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease

clinicaltrials.gov Identifier: NCT00235716.

A simulation study of the number of events per variable in logistic regression analysis

We performed a Monte Carlo study to evaluate the effect of the number of events per variable (EPV) analyzed in logistic regression analysis. The simulations were based on data f...

Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury

Intensive renal support in critically ill patients with acute kidney injury did not decrease mortality, improve recovery of kidney function, or reduce the rate of nonrenal organ...