B-Cell Clones as Early Markers for Chronic Lymphocytic Leukemia
In peripheral blood obtained up to 77 months before a CLL diagnosis, prediagnostic B-cell clones were present in 44 of 45 patients with CLL.
In peripheral blood obtained up to 77 months before a CLL diagnosis, prediagnostic B-cell clones were present in 44 of 45 patients with CLL.
Key Points Low-count and high-count monoclonal B-cell lymphocytosis (MBL) have distinct immunogenetic signatures, with only the latter resembling CLL. Rather than a true premali...
Abstract The biological and clinical relationship between Chronic Lymphocytic Leukaemia (CLL) and Monoclonal B‐cell Lymphocytosis (MBL) has now been reported in some detail. Thi...
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