Mary K. Doherty - Researcher Profile

Publications

2 shown

A Random Mutagenesis Approach to Isolate Dominant-Negative Yeast<i>sec1</i>Mutants Reveals a Functional Role for Domain 3a in Yeast and Mammalian Sec1/Munc18 Proteins

Alan Boyd , Leonora F. Ciufo , Jeff W. Barclay +6 more

Abstract SNAP receptor (SNARE) and Sec1/Munc18 (SM) proteins are required for all intracellular membrane fusion events. SNAREs are widely believed to drive the fusion process, b...

2008 Genetics 46 citations

Turnover of the Human Proteome: Determination of Protein Intracellular Stability by Dynamic SILAC

Mary K. Doherty , Dean E. Hammond , Michael J. Clague +2 more

The proteome of any system is a dynamic entity, such that the intracellular concentration of a protein is dictated by the relative rates of synthesis and degradation. In this wo...

2008 Journal of Proteome Research 345 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 391
Institution: University of Liverpool

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0002-3480-4088

Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.