Positional cloning of the mouse obese gene and its human homologue
The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean. One of the molecules that regulates energy balance in the mouse ...
Publications
3 shownIncreased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.
The gene product of the recently cloned mouse obese gene (ob) is important in regulating adipose tissue mass. ob RNA is expressed specifically by mouse adipocytes in vivo in eac...
Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene
The gene product of the ob locus is important in the regulation of body weight. The ob product was shown to be present as a 16-kilodalton protein in mouse and human plasma but w...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 18,158
- Institution
- Rockefeller University
External Links
Identifiers
- ORCID
- 0000-0002-8534-2450
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.