Joshua Gould

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

<i>GSEA-P</i>: a desktop application for Gene Set Enrichment Analysis

Abstract Gene Set Enrichment Analysis (GSEA) is a computational method that assesses whether an a priori defined set of genes shows statistically significant, concordant differe...

High-definition spatial transcriptomics for in situ tissue profiling

Spatial and molecular characteristics determine tissue function, yet high-resolution methods to capture both concurrently are lacking. Here, we developed high-definition spatial...

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

To gain insight into the genomic basis of diffuse large B-cell lymphoma (DLBCL), we performed massively parallel whole-exome sequencing of 55 primary tumor samples from patients...