Crystal Structure of Human Toll-Like Receptor 3 (TLR3) Ectodomain
Toll-like receptors (TLRs) play key roles in activating immune responses during infection. The human TLR3 ectodomain structure at 2.1 angstroms reveals a large horseshoe-shaped ...
Publications
3 shownA highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
Targeting the SARS-CoV-2 spike The surface of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) is decorated with trimeric spikes that bind to host cell receptors. Th...
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Protective neutralizing antibodies Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neu...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 3,688
- Institution
- Scripps Research Institute
External Links
Identifiers
- ORCID
- 0000-0002-6469-2419
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.