An Induced Proximity Model for Caspase-8 Activation
The assembly of the CD-95 (Fas/Apo-1) receptor death-inducing signaling complex occurs in a hierarchical manner; the death domain of CD-95 binds to the corresponding domain in t...
Publications
3 shownCaspase-9 Can Be Activated without Proteolytic Processing
The recombinant form of the proapoptotic caspase-9 purified following expression in Escherichia coli is processed at Asp315, but largely inactive; however, when added to cytosol...
Regulation of Cell Death Protease Caspase-9 by Phosphorylation
Caspases are intracellular proteases that function as initiators and effectors of apoptosis. The kinase Akt and p21-Ras, an Akt activator, induced phosphorylation of pro–caspase...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 4,621
- Institution
- Sanford Burnham Prebys Medical Discovery Institute
External Links
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.