David J. Dooling

Comprehensive molecular portraits of human breast tumours

Integrated genomic analyses of ovarian carcinoma

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Integrated genomic characterization of endometrial carcinoma

Structure, function and diversity of the healthy human microbiome

Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this...

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal evolution at the cytogenetic level. To determine the...

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and...

The genomic landscape of hypodiploid acute lymphoblastic leukemia