The Origin and Evolution of Mutations in Acute Myeloid Leukemia

John S. Welch , Timothy J. Ley , Daniel C. Link , John S. Welch , Timothy J. Ley , Daniel C. Link , Christopher A. Miller , David E. Larson , Daniel C. Koboldt , Lukas D. Wartman , Tamara Lamprecht , Fulu Liu , Jun Xia , Cyriac Kandoth , Robert S. Fulton , Michael D. McLellan , David J. Dooling , John W. Wallis , Ken Chen , Christopher Harris , Heather K. Schmidt , Joelle Kalicki-Veizer , Charles Lu , Qunyuan Zhang , Ling Lin , Michelle D. O’Laughlin , Joshua F. McMichael , Kim D. Delehaunty , Lucinda A. Fulton , Vincent Magrini , Sean McGrath , Ryan Demeter , Tammi L. Vickery , Jasreet Hundal , Lisa L. Cook , Gary W. Swift , Jerry P. Reed , Patricia A. Alldredge , Todd Wylie , Jason Walker , Mark A. Watson , Sharon E. Heath , William D. Shannon , Nobish Varghese , Rakesh Nagarajan , Jacqueline E. Payton , Jack Baty , Shashikant Kulkarni , Jeffery M. Klco , Michael H. Tomasson , Peter Westervelt , Matthew J. Walter , Timothy A. Graubert , John F. DiPersio , Li Ding , Elaine R. Mardis , Richard K. Wilson
2012 Cell 1,541 citations

Keywords

Biologyclone (Java method)Somatic evolution in cancerMyeloid leukemiaGenome instabilityGenomeGeneticsMutationExomeHaematopoiesisExome sequencingChromothripsisMyeloidLeukemiaStem cellKaryotypeCancerCancer researchGeneChromosomeDNADNA damage

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Year
2012
Type
article
Volume
150
Issue
2
Pages
264-278
Citations
1541
Access
Closed

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John S. Welch, Timothy J. Ley, Daniel C. Link et al. (2012). The Origin and Evolution of Mutations in Acute Myeloid Leukemia. Cell , 150 (2) , 264-278. https://doi.org/10.1016/j.cell.2012.06.023

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DOI
10.1016/j.cell.2012.06.023