David A. Lewis

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Genes overlap across psychiatric disease Many genome-wide studies have examined genes associated with a range of neuropsychiatric disorders. However, the degree to which the gen...

Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

INTRODUCTION Our understanding of the pathophysiology of psychiatric disorders, including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD), lags be...

Comprehensive functional genomic resource and integrative model for the human brain

INTRODUCTION Strong genetic associations have been found for a number of psychiatric disorders. However, understanding the underlying molecular mechanisms remains challenging. R...