Charles E. McCulloch

Variance Components

Chronic Kidney Disease and the Risks of Death, Cardiovascular Events, and Hospitalization

An independent, graded association was observed between a reduced estimated GFR and the risk of death, cardiovascular events, and hospitalization in a large, community-based pop...

Elevated Blood Pressure and Risk of End-stage Renal Disease in Subjects Without Baseline Kidney Disease

Even relatively modest elevation in blood pressure is an independent risk factor for ESRD. The observed relationship does not appear to be due to confounding by clinically evide...

Generalized, Linear, and Mixed Models

An accessible and self-contained introduction to statistical models-now in a modernized new editionGeneralized, Linear, and Mixed Models, Second Edition provides an up-to-date t...

Relaxing the Rule of Ten Events per Variable in Logistic and Cox Regression

The rule of thumb that logistic and Cox models should be used with a minimum of 10 outcome events per predictor variable (EPV), based on two simulation studies, may be too conse...