Induction of the growth inhibitor IGF-binding protein 3 by p53
Transcriptional activation of target genes represents an important component of the tumour-suppressor function of p53 and provides a functional link between p53 and various grow...
Publications
3 shownCommon Pathogenetic Mechanism for Three Tumor Types in Bilateral Acoustic Neurofibromatosis
Bilateral acoustic neurofibromatosis (BANF) is a genetic defect associated with multiple tumors of neural crest origin. Specific loss of alleles from chromosome 22 was detected ...
Repression of the basal c-fos promoter by wild-type p53
Mutations in the p53 gene are the most common genetic alterations observed in many inherited and sporadic forms of human cancer. Recent studies indicate that wild-type p53 may b...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 1,224
- Institution
- Bristol-Myers Squibb (Germany)
External Links
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.