IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MAN
For years investigators have sought an assay for insulin which would combine virtually absolute specificity with a high degree of sensitivity, sufficiently exquisite for measure...
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184 publications
Sociometric Location and Innovativeness: Reformulation and Extension of the Diffusion Model
1968a class, parental encouragement and educational aspirations. American Journal of Sociology 73:559-572. 1968b Parents' education and children's educational aspirations and a...
Latent Autoimmune Diabetes Mellitus in Adults (LADA): the Role of Antibodies to Glutamic Acid Decarboxylase in Diagnosis and Prediction of Insulin Dependency
Type 1 diabetes mellitus in adults may present in a manner similar to that of Type 2 diabetes but with a late development of insulin dependency. We studied 65 patients who prese...
Fast procedure for reconstruction of full‐atom protein models from reduced representations
Abstract We introduce PULCHRA, a fast and robust method for the reconstruction of full‐atom protein models starting from a reduced protein representation. The algorithm is parti...
Nested by design: model fitting and interpretation in a mixed model era
Summary Nested data structures are ubiquitous in the study of ecology and evolution, and such structures need to be modelled appropriately. Mixed‐effects models offer a powerful...
Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling
We examined the gene expression profiles of two independent cohorts of patients with acute myeloid leukemia [n=247 and n=214 (younger than or equal to 60 years)] to study the ap...
Hormone Therapy Failure in Human Prostate Cancer: Analysis by Complementary DNA and Tissue Microarrays
The combination of cDNA and tissue microarray technologies enables rapid identification of genes associated with progression of prostate cancer to the hormone-refractory state a...
Development of a Companion Diagnostic PD-L1 Immunohistochemistry Assay for Pembrolizumab Therapy in Non–Small-cell Lung Cancer
A companion diagnostic assay was codeveloped by Dako for pembrolizumab non–small-cell lung cancer clinical trials to detect PD-L1 expression by immunohistochemistry (IHC). This ...
Single Versus Combined Blood Pressure Components and Risk for Cardiovascular Disease
Background— The utility of single versus combined blood pressure (BP) components in predicting cardiovascular disease (CVD) events is not established. We compared systolic BP (S...