Publications

Structure, Function, and Evolution of Coronavirus Spike Proteins

The coronavirus spike protein is a multifunctional molecular machine that mediates coronavirus entry into host cells. It first binds to a receptor on the host cell surface throu...

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.

17,187 patients entering 417 hospitals up to 24 hours (median 5 hours) after the onset of suspected acute myocardial infarction were randomised, with placebo control, between: (...

Simple means to improve the interpretability of regression coefficients

Summary 1. Linear regression models are an important statistical tool in evolutionary and ecological studies. Unfortunately, these models often yield some uninterpretable estima...

Self-projection and the brain

Efficient inorganic–organic hybrid heterojunction solar cells containing perovskite compound and polymeric hole conductors

Inorganic-organic hybrid structures have become innovative alternatives for next-generation dye-sensitized solar cells, because they combine the advantages of both systems. Here...

Bats Are Natural Reservoirs of SARS-Like Coronaviruses

Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here w...

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles

Secreted membrane‐enclosed vesicles, collectively called extracellular vesicles (EVs), which include exosomes, ectosomes, microvesicles, microparticles, apoptotic bodies and oth...

Wnt signaling: a common theme in animal development

Wnt proteins are now recognized as one of the major families of developmentally important signaling molecules, with mutations in Wnt genes displaying remarkable phenotypes in th...

Repeatability for Gaussian and non‐Gaussian data: a practical guide for biologists

Repeatability (more precisely the common measure of repeatability, the intra‐class correlation coefficient, ICC) is an important index for quantifying the accuracy of measuremen...

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-lik...

CONFRONTING MULTICOLLINEARITY IN ECOLOGICAL MULTIPLE REGRESSION

The natural complexity of ecological communities regularly lures ecologists to collect elaborate data sets in which confounding factors are often present. Although multiple regr...

Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19), is an emerging health threat.1 Until February 20...